Performance Analysis of an Optoelectronic Localization System for Monitoring Brain Lesioning with Proton Beams

Monitoring of the target position relative to the beam delivery system is a crucial requirement for creating small functional lesions in the brain with any radiosurgery modality. We have studied the performance of an optoelectronic localization system for monitoring brain lesioning with narrow proton beams. The system consists of three high-resolution cameras and dedicated software to locate a marker set in space. We tested the accuracy of the system by performing marker distance measurements and monitoring prescribed marker shifts with two different camera configurations and four different calibration techniques. Our results show that the camera-based alignment system appears adequate for the proposed task.