Lab-on-a-chip sensor for point-of-care measurement of manganese exposure

Author

Jothimuthu, Preetha ; Haynes, Erin N. ; Papautsky, Ian

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Cincinnati, Cincinnati, OH, USA

fYear

2009

fDate

21-25 June 2009

Firstpage

1846

Lastpage

1848

Abstract

This paper reports on the development of a lab-on-achip (LOC) sensor for rapid electrochemical point-of-care (POC) measurement of biological exposure to manganese (Mn). The sensor was fabricated using an electrodeposited bismuth film as a working electrode, and Ag/AgCl reference and Au auxiliary electrodes. Measurement of Mn was demonstrated in the 0.9 nM - 9 muM range in blood using square wave stripping voltammetry (SWSV). The sensitivity was approximately 0.5 muA/nM.

Keywords

bismuth; blood; electrochemical sensors; electrodeposits; gold; lab-on-a-chip; manganese; voltammetry (chemical analysis); Au auxiliary electrodes; Bi-Ag-AgCl-Au; Mn; biological exposure; blood; electrode; electrodeposited bismuth film; lab-on-a-chip sensor; manganese exposure; point-of-care measurement; rapid electrochemical POC measurement; size 0.9 nm to 9 mum; square wave stripping voltammetry; Biosensors; Bismuth; Blood; Electrodes; Fabrication; Gold; Lab-on-a-chip; Lithography; Manganese; Silver; Manganese; bismuth; heavy metals; lab-on-a-chip; stripping voltammetry;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009. International

Conference_Location

Denver, CO

Print_ISBN

978-1-4244-4190-7

Electronic_ISBN

978-1-4244-4193-8

Type

conf

DOI

10.1109/SENSOR.2009.5285705

Filename

5285705