DocumentCode :
1867516
Title :
A study of long-range correlations in schizophrenia EEG using detrended fluctuation analysis
Author :
Raghavendra, B.S. ; Dutt, D. Narayana
Author_Institution :
Dept. of Electr. Commun. Eng., Indian Inst. of Sci., Bangalore, India
fYear :
2010
fDate :
18-21 July 2010
Firstpage :
1
Lastpage :
5
Abstract :
In this paper, we have studied electroencephalogram (EEG) activity of schizophrenia patients, in resting eyes closed condition, with detrended fluctuation analysis (DFA). The DFA gives information about scaling and long-range correlations in time series. We computed DFA exponents from 30 scalp locations of 18 male neuroleptic-naïve, recent-onset schizophrenia (NRS) subjects and 15 healthy male control subjects. Our results have shown two scaling regions in all the scalp locations in all the subjects, with different slopes, corresponding to two scaling exponents. No significant differences between the groups were found with first scaling exponent (short-range). However, the second scaling exponent (long-range) were significantly lower in control subjects at all scalp locations (p<;0.05, Kruskal-Wallis test). These findings suggest that the long-range scaling behavior of EEG is sensitive to schizophrenia, and this may provide an additional insight into the brain dysfunction in schizophrenia.
Keywords :
behavioural sciences; diseases; electroencephalography; fluctuations; neurophysiology; time series; brain dysfunction; detrended fluctuation analysis; electroencephalogram activity; first scaling exponent; long range correlations; neuroleptic naive schizophrenia; recent onset schizophrenia; resting eyes closed condition; schizophrenia EEG; second scaling exponent; time series; Correlation; Doped fiber amplifiers; Electrodes; Electroencephalography; Fluctuations; Scalp; Time series analysis;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Signal Processing and Communications (SPCOM), 2010 International Conference on
Conference_Location :
Bangalore
Print_ISBN :
978-1-4244-7137-9
Type :
conf
DOI :
10.1109/SPCOM.2010.5560539
Filename :
5560539
Link To Document :
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