Title :
Computer-aided assessment of vascular reactivity in subjects with essential hypertension
Author :
Chilukuri, Madhu B. ; Susawa, Takashi ; Yerby, Anne B. ; Zhang, Li-Qun ; Zimmer, Julia A. ; Robertson, Rose M. ; Collins, Jerry C.
Author_Institution :
Vanderbilt Univ., Nashville, TN, USA
Abstract :
A computer-based system for acquiring and analyzing physiological signals (ECG, heart rate, systemic arterial pressure, and forearm volume) was developed. This system is used to assess the effect of dietary sodium and calcium manipulations on forearm blood flow and vascular resistance (derived from arterial pressure and forearm volume changes during brief venous occlusion) during response to autonomic stimuli (cold pressor, handgrip, mental stress, reactive hyperemia) and adrenegic agonists (isoproterenol and phenylephrine). Results from seven baseline studies prior to dietary change indicate that data acquisition is rapid and precise
Keywords :
cardiology; computerised signal processing; data acquisition; electrocardiography; haemodynamics; medical diagnostic computing; ECG; adrenegic agonists; autonomic stimuli; baseline studies; brief venous occlusion; cold pressor; computer aided assessment; computer-based system; data acquisition; dietary Ca manipulations; dietary Na; dietary change; essential hypertension; forearm blood flow; forearm volume; handgrip; heart rate; isoproterenol; mental stress; phenylephrine; physiological signals; reactive hyperemia; systemic arterial pressure; vascular reactivity; vascular resistance; Biomedical computing; Blood flow; Blood pressure; Calcium; Data acquisition; Electrocardiography; Fluid flow measurement; Heart rate; Hypertension; Immune system;
Conference_Titel :
Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in
Conference_Location :
Seattle, WA
DOI :
10.1109/IEMBS.1989.96559
