DocumentCode
191053
Title
Detection of genetic relatedness between viral samples using EM-based clustering of next-generation sequencing data
Author
Skums, Pavel ; Artyomenko, Alexander ; Glebova, Olga ; Zelikovsky, Alexander ; Campo, David S. ; Dimitrova, Zoya ; Khudyakov, Yury
Author_Institution
Centers of Disease Control & Prevention, Atlanta, GA, USA
fYear
2014
fDate
2-4 June 2014
Firstpage
1
Lastpage
1
Abstract
We present a novel general tool for highly sensitive detection of genetic relatedness between highly heterogeneous viral samples based on the clustering of next-generation sequencing data. The tool may be used for detection of viral transmissions and outbreaks and for laboratory quality control.
Keywords
diseases; epidemics; genetics; genomics; microorganisms; EM-based clustering; genetic relatedness detection; heterogeneous viral samples; laboratory quality control; next-generation sequencing data; viral outbreak detection; viral transmission detection; Electronic mail; Genetics; Next generation networking; Quality control; Sequential analysis; Sociology; Statistics;
fLanguage
English
Publisher
ieee
Conference_Titel
Computational Advances in Bio and Medical Sciences (ICCABS), 2014 IEEE 4th International Conference on
Conference_Location
Miami, FL
Print_ISBN
978-1-4799-5786-6
Type
conf
DOI
10.1109/ICCABS.2014.6863938
Filename
6863938
Link To Document