Neural signal changes associated with cardiac and respiratory measures vs boxcar analysis in functional magnetic resonance imaging (fMRI)

Author

Macey, K.E. ; Macey, P.M. ; Woo, M.A. ; Henderson, L.A. ; Frysinger, R.C. ; Alger, J.R. ; Harper, R.M.

Author_Institution

Dept. of Neurology, California Univ., Los Angeles, CA, USA

Volume

3

fYear

2001

fDate

2001

Firstpage

2315

Abstract

Functional magnetic resonance imaging (fMRl) was used to measure signal changes in the brain during a respiratory challenge that elevated blood pressure. Subjects were scanned during a baseline period and during a Valsalva maneuver. Results were compared using fixed-effects analysis with the SPM99 package, and examined once using a boxcar model and once by models generated from changes in cardiac and respiratory signals during the breathing challenge. Models based on physiological measures resulted in greater localization of signal changes.

Keywords

biocontrol; biomedical MRI; brain; cardiology; diseases; haemodynamics; medical image processing; neurophysiology; pneumodynamics; statistical analysis; SPM99 package; Valsalva maneuver; baseline period; boxcar analysis; brain; breathing challenge; cardiac measures; disease conditions; elevated blood pressure; fMRI; fixed-effects analysis; functional magnetic resonance imaging; neural signal changes; normal conditions; obstructive sleep apnea; physiological measures; respiratory measures; signal change localization; Biomedical monitoring; Blood pressure; Heart rate; Image analysis; Magnetic analysis; Magnetic resonance imaging; Medical services; Radiology; Signal analysis; Signal design;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE

ISSN

1094-687X

Print_ISBN

0-7803-7211-5

Type

conf

DOI

10.1109/IEMBS.2001.1017239

Filename

1017239