Title :
Modulation of paired-pulse responses in the dentate gyrus: vigilance state effects
Author :
Blaise, J. Harry ; Bronzino, Joseph D. ; Morgane, Peter J.
Author_Institution :
Biomed. Eng. Graduate Program, Connecticut Univ., Storrs, CT, USA
Abstract :
This study was undertaken to assess the effects of vigilance state on measures of the paired-pulse response recorded in the dentate granule cell layer of the hippocampal formation in freely moving rats. Paired-pulse stimulation of the medial perforant pathway was used to construct a paired-pulse index (PPI) for 15-, 30- and 90-day old animals during the vigilance states of quiet waking, slow-wave sleep, and rapid eye movement sleep. Results indicate that at each age there is no significant difference in PPI values across the range of interpulse intervals selected
Keywords :
bioelectric potentials; brain; cellular biophysics; neurophysiology; sleep; 0.041 to 0.246 y; dentate gyrus; freely moving rats; hippocampal formation; interpulse intervals; paired-pulse index; paired-pulse responses modulation; quiet waking; rapid eye movement sleep; slow-wave sleep; vigilance state effects; Biomedical engineering; Biomedical measurements; Educational institutions; Electrodes; Feedforward systems; Pulse amplifiers; Rats; Signal analysis; Sleep; Space vector pulse width modulation;
Conference_Titel :
Bioengineering Conference, 1998. Proceedings of the IEEE 24th Annual Northeast
Conference_Location :
Hershey, PA
Print_ISBN :
0-7803-4544-4
DOI :
10.1109/NEBC.1998.664856
