Title :
In vivo Raman spectroscopy for early lung cancer detection
Author :
Zeng, Haishan ; Short, Michael A. ; McWilliams, Annette ; Lam, Stephen
Author_Institution :
Cancer Imaging Dept., British Columbia Cancer Res. Centre, Vancouver, BC, Canada
Abstract :
We developed a fast dispersive-type near-infrared in vivo Raman spectroscopy system for improving early detection of lung cancers. We have measured spectra from 50 patients. Combined principal component analysis and linear discriminate analysis of the acquired data demonstrated that malignant and benign lesions can be differentiated with around 90% accuracy.
Keywords :
Raman spectroscopy; cancer; infrared spectroscopy; laser applications in medicine; lung; patient diagnosis; principal component analysis; benign lesions; early lung cancer detection; fast dispersive type spectroscopy system; in vivo Raman spectroscopy; linear discriminate analysis; malignant lesions; near infrared spectroscopy system; principal component analysis;
Conference_Titel :
Communications and Photonics Conference and Exhibition (ACP), 2010 Asia
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-7111-9
DOI :
10.1109/ACP.2010.5682615
