DocumentCode :
1988687
Title :
Prediction of protein function using signal processing of biochemical properties
Author :
Gopalakrishnan, Krishna ; Najarian, Kayvan
Author_Institution :
Dept. of Comput. Sci., North Carolina Univ., Charlotte, NC, USA
fYear :
2003
fDate :
11-14 Aug. 2003
Firstpage :
536
Lastpage :
538
Abstract :
We present a technique to find the biological function of protein from its primary sequence. Currently used protein classification methods make use of multiple alignments. We use signal-processing features obtained from the primary sequence of the protein, to predict its biological function. The primary sequence of protein is converted to signals based on the encoding of biochemical properties like hydrophobicity, solubility, molecular weight of constituent amino acids. Signal processing features like complexity, mobility and fractal dimension are extracted from the obtained signals. Studies are conducted for lipase, protease and isomerase of length between 100 and 200 amino acids.
Keywords :
biochemistry; molecular biophysics; molecular weight; organic compounds; proteins; signal processing; solubility; amino acids; biochemical property; biological function; complexity; encoding; fractal dimension; hydrophobicity; isomerase; lipase; mobility; molecular weight; multiple alignments; primary sequence; protease; proteins; signal-processing feature; solubility; Amino acids; Biochemical analysis; Biological information theory; Biomedical signal processing; Computer science; Encoding; Fractals; Proteins; Sequences; Signal processing;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioinformatics Conference, 2003. CSB 2003. Proceedings of the 2003 IEEE
Print_ISBN :
0-7695-2000-6
Type :
conf
DOI :
10.1109/CSB.2003.1227400
Filename :
1227400
Link To Document :
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