Title :
Exact and heuristic algorithms for the DNA fragment assembly problem
Author :
Jing, Yimin ; Khuri, Sami
Author_Institution :
Dept. of Comput. Sci., San Jose State Univ., CA, USA
Abstract :
As more and more public and private genomic assemblies are available, the need for comparison of different computation methods used in the DNA fragment assembly becomes apparent. In this work, we design, implement, and test four heuristic algorithms for assembling DNA fragments. We also design, implement and test an exact algorithm to solve the fragment assembly problem.
Keywords :
DNA; biocomputing; dynamic programming; genetic algorithms; heuristic programming; molecular biophysics; DNA fragment assembly problem; computation methods; exact algorithm; genomic assembly; heuristic algorithm; Assembly systems; Bioinformatics; DNA computing; Heuristic algorithms;
Conference_Titel :
Bioinformatics Conference, 2003. CSB 2003. Proceedings of the 2003 IEEE
Print_ISBN :
0-7695-2000-6
DOI :
10.1109/CSB.2003.1227413