DocumentCode
1995568
Title
Control and reversal of tumor growth by ultrasound activated microbubbles
Author
Chin, Chien Ting ; Raju, Balasundar I. ; Shevchenko, Talent ; Klibanov, Alexander L.
Author_Institution
Ultrasound Imaging & Therapy, Philips Res. North America, Briarcliff Manor, NY, USA
fYear
2009
fDate
20-23 Sept. 2009
Firstpage
77
Lastpage
80
Abstract
It has been known that tumor insonation after intravenous microbubble injection may lead to transient reduction of tumor blood flow. Subsequent experiments showed that repeated induction of tumor blood flow disruption may retard tumor growth. This paper reports an initial investigation of the underlying blood flow disruption phenomena and the first systematic investigation of the control of tumor growth by the combination of moderately intense ultrasound and microbubbles.
Keywords
biomedical ultrasonics; haemodynamics; radiation therapy; tumours; blood flow disruption; intravenous microbubble injection; microbubbles; tumor blood flow; tumor growth; tumor insonation; Blood flow; Cardiology; Control systems; Lipidomics; Medical treatment; Mice; Neoplasms; North America; Protocols; Ultrasonic imaging; microbubbles; perfusion; therapy; tumor;
fLanguage
English
Publisher
ieee
Conference_Titel
Ultrasonics Symposium (IUS), 2009 IEEE International
Conference_Location
Rome
ISSN
1948-5719
Print_ISBN
978-1-4244-4389-5
Electronic_ISBN
1948-5719
Type
conf
DOI
10.1109/ULTSYM.2009.5441604
Filename
5441604
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