Application of three dimensional image analysis to the mammalian cell nucleus

Author

Samarabandu, J. ; Cheng, P.C. ; Berezney, R.

Author_Institution

Dept. of Biophys. Sci., State Univ. of New York, Buffalo, NY, USA

fYear

1994

fDate

10-13 Apr 1994

Firstpage

98

Lastpage

100

Abstract

A three dimensional image segmentation and analysis system is proposed to study the confocal microscopy images of DNA replication sites in cell nuclei. The algorithm presented here includes detection of replication sites in 2D slices in the image and reconstructing 3D objects from 2D data. We also present a user interface to allow easy interaction with both the segmentation algorithm and the 3D segmented data

Keywords

DNA; biology computing; image reconstruction; image segmentation; medical image processing; user interfaces; 2D data; 2D slices; 3D object reconstruction; 3D segmented data; DNA replication sites; cell nuclei; confocal microscopy images; mammalian cell nucleus; replication site detection; segmentation algorithm; three dimensional image analysis; three dimensional image segmentation; user interface; Biology; Cells (biology); DNA; Data mining; Fibroblasts; Image analysis; Image segmentation; Mice; Microscopy; Pattern analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Southeastcon '94. Creative Technology Transfer - A Global Affair., Proceedings of the 1994 IEEE

Conference_Location

Miami, FL

Print_ISBN

0-7803-1797-1

Type

conf

DOI

10.1109/SECON.1994.324274

Filename

324274