Algorithm for an implantable fluorescence based glucose sensor

Author

Xiaolin Wang ; Mdingi, C. ; DeHennis, A. ; Colvin, A.E.

Author_Institution

Sensors for Med. & Sci., Inc., Germantown, MD, USA

fYear

2012

fDate

Aug. 28 2012-Sept. 1 2012

Firstpage

3492

Lastpage

3495

Abstract

This article describes the algorithm for a continuous glucose monitor (CGM). The CGM system consists of an external reader and an insertable fluorescence based sensor. The sensor consists of a miniaturized optical sensor that incorporates a biocompatible macromolecular indicator that selectively binds glucose. It is designed to be subcutaneously inserted and allows for the direct measurement of interstitial fluid (ISF) glucose.

Keywords

biomedical equipment; biomedical measurement; biosensors; blood; fluorescence; macromolecules; molecular biophysics; optical sensors; patient monitoring; biocompatible macromolecular indicator; continuous glucose monitoring; external reader; implantable fluorescence based glucose sensor algorithm; insertable fluorescence based sensor; interstitial fluid glucose measurement; miniaturized optical sensor; Equations; Fluorescence; Sugar; Temperature measurement; Temperature sensors; Thermal degradation; Tin; Algorithms; Biosensing Techniques; Blood Glucose; Diabetes Mellitus, Type 1; Fluorescence; Humans; Miniaturization;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE

Conference_Location

San Diego, CA

ISSN

1557-170X

Print_ISBN

978-1-4244-4119-8

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/EMBC.2012.6346718

Filename

6346718