DOI and fMRI coupling study across scanners

Recent advances have provided a more accurate model for the coupling between the hemodynamic signal, as measured by diffuse optical imaging (DOI) and functional magnetic resonance imaging (fMRI), and its underlying neural electrical activity. We describe here a new strategy, which is grounded in conformal geometry, for automated labelling in order to provide a greater accuracy for anatomical localization in single subject across scanners and modalities. We examine how these results, together with the current insights reported in the literature, might provide a more secure basis for extracting functional information from functional images, and to permit optimization of functional imaging protocols across scanners.