High sensitive circular Hall Effect sensor for magnetic bead labeled immunoassay

Author

Zhang, Bowei ; Korman, Can E. ; Zaghloul, Mona E.

Author_Institution

Inst. of MEMS &VLSI Technol., George Washington Univ., Washington,DC USA

fYear

2010

fDate

1-4 Nov. 2010

Firstpage

1578

Lastpage

1582

Abstract

A novel circular shape CMOS Hall Effect sensor design is proposed in this paper. Compared with traditional rectangular shape Hall Effect sensor, the proposed design can improve the sensitivity significantly. By implementing this sensor design with readout circuit, amplifier and DSP circuit in a CMOS chip, the Enzyme-Linked Immunosorbent Assay (ELISA) can be replaced by a lower cost, more portable and higher sensitive magnetic bead labeled immunoassay platform, which could eventually realize molecular diagnosis on chip.

Keywords

CMOS integrated circuits; Hall effect; biomedical electronics; biosensors; enzymes; magnetic sensors; DSP circuit; ELISA; Enzyme-Linked Immunosorbent Assay; amplifier; circular shape CMOS Hall effect sensor design; high sensitive circular Hall effect sensor; magnetic bead labeled immunoassay; molecular diagnosis; readout circuit; CMOS integrated circuits; CMOS technology; Hall effect; Magnetic fields; Magnetic resonance imaging; Sensitivity; Shape; CMOS; Hall Effect Sensor; Molecular Diagnosis;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2010 IEEE

Conference_Location

Kona, HI

ISSN

1930-0395

Print_ISBN

978-1-4244-8170-5

Electronic_ISBN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2010.5690291

Filename

5690291