• DocumentCode
    2136117
  • Title

    Predicting RNA-protein interactions using a novel method

  • Author

    Tong Wang ; Hongmei Li ; Xiaoming Hu ; Xiaoxia Cao

  • Author_Institution
    Inst. of Comput. & Inf., Shanghai Second Polytech. Univ., Shanghai, China
  • fYear
    2012
  • fDate
    16-18 Oct. 2012
  • Firstpage
    981
  • Lastpage
    985
  • Abstract
    Given the sequence of a protein, a biologist may wish to know whether it interacts with a given RNA sequence or not. Protein-RNA interactions play an important role in a number of fundamental cellular processes, such as RNA splicing, transport and translation, protein synthesis and certain RNA-mediated enzymatic processes. In this paper, novel feature extraction methods are proposed to predict protein-RNA interactions with a SVM classifier. The results indicate that the performance of the feature extraction method is superior to other approaches.
  • Keywords
    RNA; biology computing; feature extraction; molecular biophysics; pattern classification; proteins; support vector machines; SVM classifier; feature extraction; protein-RNA interactions; RNA-protein interaction; feature extraction method; sequence encoding scheme;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Engineering and Informatics (BMEI), 2012 5th International Conference on
  • Conference_Location
    Chongqing
  • Print_ISBN
    978-1-4673-1183-0
  • Type

    conf

  • DOI
    10.1109/BMEI.2012.6513097
  • Filename
    6513097