DocumentCode
2136703
Title
High sensitivity biosensing using nano-slot nanolaser
Author
Kita, Shota ; Hachuda, Shoji ; Baba, Toshihiko ; Endo, Tatsuro ; Nishijima, Yoshiaki ; Misawa, Hiroaki
Author_Institution
Dept. of Electr. & Comput. Eng., Yokohama Nat. Univ., Yokohama, Japan
fYear
2010
fDate
1-4 Nov. 2010
Firstpage
2303
Lastpage
2306
Abstract
We have developed photonic crystal nanolaser and applied it to sensing liquids and bio-molecules. In this study, a nano-slot structure is introduced into the nanolaser, which strengthens the mode localization and improves the sensitivity, stability, and resolution as a sensor. As a result, a very low detection limit of 5.1 pg/ml has been achieved for BSA protein. It will be applicable to high-throughput label-free biosensing, while a mechanism of such low detection limit with the nano-slot is of great interest to investigate.
Keywords
biosensors; nanobiotechnology; photonic crystals; proteins; BSA protein; high sensitivity biosensing; mode localization; nanoslot nanolaser; photonic crystal nanolaser; sensor resolution; sensor stability;
fLanguage
English
Publisher
ieee
Conference_Titel
Sensors, 2010 IEEE
Conference_Location
Kona, HI
ISSN
1930-0395
Print_ISBN
978-1-4244-8170-5
Electronic_ISBN
1930-0395
Type
conf
DOI
10.1109/ICSENS.2010.5690745
Filename
5690745
Link To Document