A custom mixed signal CMOS integrated circuit for high performance PET tomograph front-end applications

A custom mixed-signal CMOS integrated circuit has been developed for high performance PET tomograph front-end applications. The ASIC contains four differential, variable-gain, constant bandwidth, amplifiers to receive buffered PMT voltage pulses. All four amplified PMT signals are summed by adding their outputs and feeding this sum to the timing channel of the ASIC. The timing channel, which consists of a constant fraction discriminator and sub-nanosecond time to digital converter, offers excellent PET count rate performance and random noise reduction through low deadtime (100 ns) and excellent tuning resolution (312.5 ps). Amplified PMT signals are also distributed to energy processing channels for lowpass filtering, and buffering for subsequent digitization by external ADCs. The ASIC offers substantial size, power, and cost reductions over existing PET front-end discrete designs. Fabricated in a 5 V, 0.5 μm, triple metal, double poly, n-well CMOS process, the new ASIC has a die size of 20 mm² and dynamic power dissipation under 425 mW.