Title :
Influence of low-frequency rTMS on EEG of epileptic rats
Author :
Guanghao, Zhang ; Linxia, Li ; Huo Xiaolin ; Tao, Song
Author_Institution :
Chinese Acad. of Sci., Beijing
Abstract :
The present research was to study the influence of low-frequency rTMS on epilepsy by EEG analysis. A train of 100, 0.5 Hz rTMS was applied on 15 Sprague-Dawley rats, and sham stimulation was also applied. EEG was recorded before stimulation and within 1 minute after rTMS and sham stimulation. Results showed that mean absolute power (MAP) of gamma band and relative power (RP) of beta and gamma band decreased significantly after low-frequency rTMS. In another experiment, pentylenetetrazol was injected immediately after 100 impulses of 0.5 Hz rTMS. Results showed that seizure susceptibility decreased greatly. These results indicate that low-frequency rTMS has certain suppressive effects on epilepsy due to power spectrum reduction.
Keywords :
biomagnetism; diseases; electroencephalography; EEG; Sprague-Dawley rats; electroencephalography; epileptic rats; frequency 0.5 Hz; low frequency rTMS; mean absolute power; power spectrum; repetitive transcranial magnetic stimulation; Bones; Cerebral cortex; Coils; Electroencephalography; Epilepsy; Frequency; Magnetic fields; Magnetic stimulation; Psychology; Rats;
Conference_Titel :
Noninvasive Functional Source Imaging of the Brain and Heart and the International Conference on Functional Biomedical Imaging, 2007. NFSI-ICFBI 2007. Joint Meeting of the 6th International Symposium on
Conference_Location :
Hangzhou
Print_ISBN :
978-1-4244-0949-5
Electronic_ISBN :
978-1-4244-0949-5
DOI :
10.1109/NFSI-ICFBI.2007.4387769
