Title :
Emerging Nanostructures and Devices for Diagnostics and Therapeutics
Author :
Aslam, M. ; Dravid, Vinayak P. ; Sharma, S. ; Shekhawat, G. ; Meade, T. ; Tark, S.
Author_Institution :
Northwestern Univ., Evanston
Abstract :
We are combining advances in materials synthesis, microfabrication, biology and engineering to develop multiplexed engineered platforms for bio-diagnostics and non-invasive imaging using nanostructured materials. On one front, we have developed a completely electronic signal transduction scheme for specific biomolecular binding events on microcantilever platform. Such label-and optics-free detection approach for biochemical analytes promises a widely affordable versatile diagnostics system. We are also developing complex multifunctional architecture based on magnetic nanostructures for MR imaging and therapeutics. The core philosophy of our approach is the merger and synergy of physical sciences, engineering and biology, which promise to open new vistas for advanced imaging, diagnostics and therapeutic systems.
Keywords :
biochemistry; biomedical MRI; biomedical materials; nanobiotechnology; patient treatment; MR imaging; bio-diagnostics; biochemical analytes; biomolecular binding events; electronic signal transduction scheme; magnetic nanostructures; microcantilever platform; microfabrication; nanostructured materials; non-invasive imaging; optics-free detection; therapeutics; Biochemical analysis; Biological materials; Biology; Biomedical optical imaging; Nanostructured materials; Nanostructures; Optical detectors; Optical imaging; Optical materials; Signal synthesis;
Conference_Titel :
Sensors, 2007 IEEE
Conference_Location :
Atlanta, GA
Print_ISBN :
978-1-4244-1261-7
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2007.4388319