Title :
Novel one-dimensional Mn—Fe oxide nanowires for cell labeling and magnetic resonance imaging
Author :
Leung, Ken Cham-Fai ; Wang, Yi-Xiang ; Wang, Hao-Hao ; Chak, Chun-Pong
Author_Institution :
Dept. of Chem., Chinese Univ. of Hong Kong, Hong Kong
Abstract :
Novel one-dimensional Mn-Fe oxide nanowires, which were prepared by a ligand-induced self-organization of Mn-Fe oxide nanoparticles, were employed as contrast agents for magnetic resonance imaging and cell labeling. The magnetic properties of the nanowires were characterized by a 1.5 Tesla whole body magnetic resonance imaging (MRI) machine, which revealed a substantial change in MRI signal at particle concentration of 100 mug/mL, and considerably change in MRI signal at particle concentration of 10 mug/mL. After incubation in vitro, the nanowires were effectively incorporated into the macrophage cells.
Keywords :
biological techniques; biomedical MRI; cellular biophysics; iron compounds; manganese compounds; nanobiotechnology; nanowires; MnFeO; cell labeling; incubation in vitro; ligand-induced self-organization; macrophage cells; magnetic resonance imaging; one-dimensional nanowires; oxide nanoparticles; particle concentration; Iron; Labeling; Magnetic devices; Magnetic materials; Magnetic resonance imaging; Magnetic separation; Nanoparticles; Nanostructured materials; Nanostructures; Nanowires;
Conference_Titel :
Information Technology and Applications in Biomedicine, 2008. ITAB 2008. International Conference on
Conference_Location :
Shenzhen
Print_ISBN :
978-1-4244-2254-8
Electronic_ISBN :
978-1-4244-2255-5
DOI :
10.1109/ITAB.2008.4570580
