• DocumentCode
    2230404
  • Title

    Label-free and high-throughput screening of biomolecular interactions

  • Author

    Ozkumur, I. Emre ; Needham, James ; Bergstein, David Alan ; Ruane, Michael ; Goldberg, Bennett B. ; Unlu, M. Selim

  • Author_Institution
    Dept. of Electr. & Comput. Eng., Boston Univ., Boston, MA
  • fYear
    2008
  • fDate
    4-9 May 2008
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    We present a simple label-free multi-analyte detection technique that is easily scalable for high-throughput screening. We have shown a sensitivity of 20 pg/mm2 and a minimum detectable antibody concentration of 15 ng/ml for a specific antigen.
  • Keywords
    biosensors; fibre optic sensors; molecular biophysics; antigen; biomolecular interactions; high-throughput screening; label-free multi-analyte detection technique; minimum detectable antibody concentration; Biomedical optical imaging; Fresnel reflection; Lighting; Molecular biophysics; Optical reflection; Optical refraction; Optical surface waves; Optical variables control; Reflectivity; Surface waves;
  • fLanguage
    English
  • Publisher
    iet
  • Conference_Titel
    Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
  • Conference_Location
    San Jose, CA
  • Print_ISBN
    978-1-55752-859-9
  • Type

    conf

  • Filename
    4571214
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2230404