Title :
Two-photon luminescence imaging using a MEMS-based miniaturized probe
Author :
Hoy, Christopher ; Durr, Nicholas ; Chen, Pengyuan ; Smith, Danielle K. ; Larson, Timothy ; Piyawattanametha, Wibool ; Ra, Hyejun ; Korgel, Brian ; Sokolov, Konstantin ; Solgaard, Olav ; Ben-Yakar, Adela
Author_Institution :
Dept. of Mech. Eng., Texas Univ., Austin, TX
Abstract :
We present two-photon luminescence (TPL) imaging of cancer cells through a 10 times 15 times 40 mm3 miniaturized probe employing a two-axis MEMS scanning mirror and an air-core photonic crystal fiber. The combination of TPL imaging with a small probe represents a potential method of distinguishing cancerous cells in tissue for diagnosis.
Keywords :
biomedical optical imaging; cancer; cellular biophysics; fibre optic sensors; micromirrors; microsensors; photoluminescence; photonic crystals; tumours; two-photon processes; MEMS-based miniaturized probe; air-core photonic crystal fiber; cancer cells; tissue diagnosis; two-axis MEMS scanning mirror; two-photon luminescence imaging; Cancer; Laser beams; Lenses; Luminescence; Micromechanical devices; Microscopy; Mirrors; Optical imaging; Probes; Ultrafast optics; (170.2150) Endoscopic imaging; (180.4315) Nonlinear microscopy; (250.5403) Plasmonics;
Conference_Titel :
Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-859-9
