• DocumentCode
    2248307
  • Title

    Metabolic networks analysis using convex optimization

  • Author

    Julius, A. Agung ; Imielinski, Marcin ; Pappas, George J.

  • Author_Institution
    Dept. Electr. & Syst. Eng., Univ. of Pennsylvania, Philadelphia, PA, USA
  • fYear
    2008
  • fDate
    9-11 Dec. 2008
  • Firstpage
    762
  • Lastpage
    767
  • Abstract
    Metabolic networks map the biochemical reactions in a living cell to the flow of various chemical substances in the cell, which are called metabolites. A standard model of a metabolic network is given as a linear map from the reaction rates to the change in metabolites concentrations. We study two problems related to the analysis of metabolic networks, the minimal network problem and the minimal knockout problem.
  • Keywords
    optimisation; biochemical reactions; chemical substances; convex optimization; metabolic networks analysis; metabolites concentrations; minimal knockout problem; minimal network problem; Biochemistry; Bioinformatics; Biological system modeling; Cells (biology); Cellular networks; Genomics; Organisms; Production; Steady-state; Systems biology;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Decision and Control, 2008. CDC 2008. 47th IEEE Conference on
  • Conference_Location
    Cancun
  • ISSN
    0191-2216
  • Print_ISBN
    978-1-4244-3123-6
  • Electronic_ISBN
    0191-2216
  • Type

    conf

  • DOI
    10.1109/CDC.2008.4739111
  • Filename
    4739111