• DocumentCode
    2294899
  • Title

    Non-invasive, optical monitoring and characterization of biochemical changes during stem cell differentiation

  • Author

    Quinn, K.P. ; Georgakoudi, I.

  • Author_Institution
    Dept. of Biomed. Eng., Tufts Univ., Medford, MA, USA
  • fYear
    2011
  • fDate
    18-20 May 2011
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Multi-photon excited fluorescence microscopy was utilized to monitor the biochemical changes associated with the development of silk-based engineered constructs into functional adipose tissue. Based on the intrinsic fluorescence of NADH and FAD, cells within vascularized adipose tissue demonstrated significantly higher metabolic activity than cells in non-vascularized control tissue.
  • Keywords
    bio-optics; biochemistry; cellular biophysics; fluorescence; optical microscopy; tissue engineering; biochemical change; functional adipose tissue; intrinsic fluorescence; multiphoton excited fluorescence microscopy; noninvasive monitoring; optical monitoring; silk-based engineered constructs; stem cell differentiation; Fluorescence; Imaging; In vitro; Monitoring; Pixel; Stem cells; Three dimensional displays;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information Photonics (IP), 2011 ICO International Conference on
  • Conference_Location
    Ottawa, ON
  • Print_ISBN
    978-1-61284-315-5
  • Type

    conf

  • DOI
    10.1109/ICO-IP.2011.5953743
  • Filename
    5953743