• DocumentCode
    2309928
  • Title

    Double Tilted Fiber Bragg Grating for label-free DNA detection

  • Author

    Candiani, Alessandro ; Sozzi, Michele ; Coscelli, Enrico ; Poli, Federica ; Ucinotta, Annamaria ; Selleri, Stefano ; Veneziano, Rosanna ; Corradini, Roberto ; Marchelli, Rosangela ; Childs, Paul ; Pissadakis, Stavros

  • Author_Institution
    Inf. Eng. Dept., Univ. of Parma, Parma, Italy
  • fYear
    2011
  • fDate
    8-10 June 2011
  • Firstpage
    1
  • Lastpage
    3
  • Abstract
    We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.
  • Keywords
    Bragg gratings; DNA; bio-optics; biomedical transducers; biosensors; fibre optic sensors; light interference; molecular biophysics; biofunctionalized transducers; biosensor; double tilted fiber Bragg grating; fringe visibility; interference spectrum; label-free DNA detection; real-time spectral measurement; Biosensors; Bragg gratings; DNA; Optical fiber sensors; Optical fibers; Refractive index;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    BioPhotonics, 2011 International Workshop on
  • Conference_Location
    Parma
  • Print_ISBN
    978-1-4244-9836-9
  • Electronic_ISBN
    978-1-4244-9835-2
  • Type

    conf

  • DOI
    10.1109/IWBP.2011.5954849
  • Filename
    5954849