Title :
Pharmacokinetic Model of Sustained-Release Agents
Author :
He, Wei ; Zhan, Shanshan ; Yang, QinHong ; Wang, Chengyue ; Wei Yang ; Ding, Yong ; Zheng, Yu
Author_Institution :
Dept. of Biomed. Eng., Nanjing Med. Univ., Nanjing, China
Abstract :
Based on the pharmacokinetic model of conventional agents, through introduction of sustained-release effect factor, we build a pharmacokinetic model of sustained-release agents so as to provide a new model of agents for clinical application. We discuss the properties of the new model and make a comparison with the conventional ones. By theoretical analysis and clinical data validation of metformin conventional agents and sustained-release ones, the model we build in this paper accords with the properties of sustained-release agents and it has practical value for clinical applications.
Keywords :
medicine; pharmaceuticals; pharmacokinetic model; sustained-release agents; sustained-release effect factor; Absorption; Application software; Biomedical engineering; Computational modeling; Computer simulation; Data analysis; Drugs; Helium; Mathematical model; Plasmas;
Conference_Titel :
Biomedical Engineering and Computer Science (ICBECS), 2010 International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5315-3
DOI :
10.1109/ICBECS.2010.5462309
