Title :
Finite element modelling of extracellular potentials around thin-film microelectrode probes in invertebrate peripheral nerve
Author :
Banks, D.J. ; Balachandran, W. ; Ewins, D.J. ; Hughes, S.C. ; Richards, P.R.
Author_Institution :
Dept. of Electron. & Electr. Eng., Surrey Univ., Guildford, UK
Abstract :
Thin-film microelectrode probes (microprobes) are being investigated as peripheral nerve neural signal transducers for use in functional electrical stimulation orthoses. Finite element modelling techniques have been used to determine the effects of microprobe substrates on extracellular signals recorded intraneurally from locust peripheral nerve. The models show that probes with widths of the order of one-tenth the longitudinal extent of the action potential can have effects of amplifying signals from nerve fibres in front of the probe, and attenuating signals from fibres behind. The nerve sheath can also contribute to, and modulate, these effects
Keywords :
bioelectric potentials; cellular transport; finite element analysis; microelectrodes; muscle; neurophysiology; orthotics; probes; action potential; extracellular potentials; extracellular signals; finite element modelling; functional electrical stimulation orthoses; invertebrate peripheral nerve; locust peripheral nerve; microprobe substrates; microprobes; nerve fibres; nerve sheath; peripheral nerve neural signal transducers; thin-film microelectrode probes; Conductivity; Extracellular; Finite element methods; Mechanical engineering; Microelectrodes; Neurons; Probes; Substrates; Transducers; Transistors;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415148
