Title :
Statistical dynamics of the membrane channel gating charge system
Author :
Chernyak, Yuri B.
Author_Institution :
Div. of Health Sci. & Technol., MIT, Cambridge, MA, USA
Abstract :
The membrane channel´s gating charge system is well represented as a set of strongly interacting dipoles. The equilibrium and kinetics of the system are described by the corresponding Boltzmann distribution and time dependent solutions of the Fokker-Planck equation. The theory explains very well various experiments on gating current and allows new insight in channel gating
Keywords :
Fokker-Planck equation; bioelectric phenomena; biomembrane transport; cellular biophysics; physiological models; Boltzmann distribution; gating current; membrane channel gating charge system; statistical dynamics; strongly interacting dipoles set; time dependent solutions; Biomembranes; Boltzmann distribution; Charge measurement; Current measurement; Distribution functions; Equations; Kinetic theory; Polarization; Shape; Strips;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415265
