Title :
Effect of cardiac passive properties on the time delay in modeling stunned myocardium
Author :
Wang, Jia-Jung ; Drzewiecki, Gary M. ; Li, John K-J. ; Kedem, Joseph ; Weiss, Harvey
Author_Institution :
Dept. of Biomed. Eng., Rutgers Univ., Piscataway, NJ, USA
Abstract :
The effect of mechanical passive factors on the regional time delay (TD) of fiber shortening in stunned myocardium was examined using a computer model. Experimental data showed that TDs were much longer in the stunned zone than in the prestunned and nonstunned zones. In addition, a correlation coefficient of 0.63 between TD and end-diastolic segment length in stunned myocardium was round. A computer model of the left ventricle was divided into two separate regions, normal and stunned. The model employed an exponential relationship between pressure and volume in the stunned region. It was found that when the end-diastolic volume (EDV) of the stunned region increased, passive compliance (Cp) decreased while TD increased, similar to the experimental result
Keywords :
biomechanics; EDV; cardiac passive properties; computer model; correlation coefficient; end-diastolic segment length; end-diastolic volume; exponential relationship; fiber shortening; left ventricle; mechanical passive factors; nonstunned zone; passive compliance; prestunned zone; regional time delay; stunned myocardium modeling; stunned zone; time delay; Arterial occlusion; Biomedical computing; Biomedical measurements; Cardiology; Delay effects; Dogs; Length measurement; Mechanical factors; Mechanical variables measurement; Myocardium;
Conference_Titel :
Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers. Proceedings of the 16th Annual International Conference of the IEEE
Conference_Location :
Baltimore, MD
Print_ISBN :
0-7803-2050-6
DOI :
10.1109/IEMBS.1994.415390
