DocumentCode
238567
Title
Scalable Multi-core Implementation for Motif Finding Problem
Author
Abbas, Muhammad Muddassir ; Malluhi, Qutaibah M. ; Balakrishnan, Pranav
Author_Institution
KINDI Lab. for Comput. Res., Qatar Univ., Doha, Qatar
fYear
2014
fDate
24-27 June 2014
Firstpage
178
Lastpage
183
Abstract
The motif finding problem is a key step for understanding the gene regulation and expression, drug design, disease resistance, etc. Many sequential algorithms have been proposed in the literature to find the exact motifs. Voting algorithm is one such memory and time efficient sequential solution for motif finding. In this paper, we develop a parallel version of CVoting algorithm realized using openMP. The paper evaluates this parallel algorithm on a multi-core architecture using both simulated and real datasets. The paper compares the performance against existing multi-core implementations. Our experiments show that, the scalability of our implementation is linear for all challenging instances running on different number of processors, while the scalability of other implementations varies with respect to motif length or the number of processors. The average efficiency of our parallel implementations for all instances is more than 90%.
Keywords
DNA; biology computing; genetics; multiprocessing programs; parallel algorithms; CVoting algorithm; DNA motif mapping; DNA motif prediction; disease resistance; drug design; gene expression; gene regulation; motif finding problem; motif length; multicore architecture; openMP; parallel algorithm; scalable multicore implementation; Algorithm design and analysis; Approximation algorithms; Approximation methods; DNA; Prediction algorithms; Program processors; Scalability; Voting algorithm; challenging instances; motif finding; multi-core;
fLanguage
English
Publisher
ieee
Conference_Titel
Parallel and Distributed Computing (ISPDC), 2014 IEEE 13th International Symposium on
Conference_Location
Marseilles
Print_ISBN
978-1-4799-5918-1
Type
conf
DOI
10.1109/ISPDC.2014.27
Filename
6900217
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