• DocumentCode
    238567
  • Title

    Scalable Multi-core Implementation for Motif Finding Problem

  • Author

    Abbas, Muhammad Muddassir ; Malluhi, Qutaibah M. ; Balakrishnan, Pranav

  • Author_Institution
    KINDI Lab. for Comput. Res., Qatar Univ., Doha, Qatar
  • fYear
    2014
  • fDate
    24-27 June 2014
  • Firstpage
    178
  • Lastpage
    183
  • Abstract
    The motif finding problem is a key step for understanding the gene regulation and expression, drug design, disease resistance, etc. Many sequential algorithms have been proposed in the literature to find the exact motifs. Voting algorithm is one such memory and time efficient sequential solution for motif finding. In this paper, we develop a parallel version of CVoting algorithm realized using openMP. The paper evaluates this parallel algorithm on a multi-core architecture using both simulated and real datasets. The paper compares the performance against existing multi-core implementations. Our experiments show that, the scalability of our implementation is linear for all challenging instances running on different number of processors, while the scalability of other implementations varies with respect to motif length or the number of processors. The average efficiency of our parallel implementations for all instances is more than 90%.
  • Keywords
    DNA; biology computing; genetics; multiprocessing programs; parallel algorithms; CVoting algorithm; DNA motif mapping; DNA motif prediction; disease resistance; drug design; gene expression; gene regulation; motif finding problem; motif length; multicore architecture; openMP; parallel algorithm; scalable multicore implementation; Algorithm design and analysis; Approximation algorithms; Approximation methods; DNA; Prediction algorithms; Program processors; Scalability; Voting algorithm; challenging instances; motif finding; multi-core;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Parallel and Distributed Computing (ISPDC), 2014 IEEE 13th International Symposium on
  • Conference_Location
    Marseilles
  • Print_ISBN
    978-1-4799-5918-1
  • Type

    conf

  • DOI
    10.1109/ISPDC.2014.27
  • Filename
    6900217