Title :
High-efficiency and side-viewing micro fiber optic probe for in-vivo diffuse reflectance measurements of human epithelial tissues
Author :
Garcia-Uribe, Alejandro ; Balareddy, Karthik C. ; Chang, Cheng-Chung ; Yapici, Murat K. ; Zou, Jun ; Wang, Lihong V.
Author_Institution :
Dept. of Electr. & Comput. Eng., Texas A&M Univ., College Station, TX, USA
Abstract :
In this paper, we present a new micro fiber optic probe for in-vivo diffuse reflectance measurements of human epithelial tissues. The probe consists of seven, 120times120 mum collection fibers and one 200 mum incidence source fiber, arranged into a side-viewing configuration by using curved air-core waveguides with high optical transmittance. The outer dimension of the probe is 2times8 mm2. The extremely small size, high transmission efficiency and side-viewing capability of the new probe make it suitable for endoscopic spectroscopic applications inside the human body.
Keywords :
bio-optics; biological tissues; endoscopes; fibre optic sensors; micro-optics; curved air-core waveguides; endoscopic spectroscopic applications; high optical transmittance; high transmission efficiency; human epithelial tissues; in-vivo diffuse reflectance measurements; microfiber optic probe; side-viewing configuration; size 120 mum; size 200 mum; Epithelium; Equipment Design; Equipment Failure Analysis; Fiber Optic Technology; Miniaturization; Nephelometry and Turbidimetry; Photometry; Reproducibility of Results; Sensitivity and Specificity; Skin Physiological Phenomena;
Conference_Titel :
Engineering in Medicine and Biology Society, 2009. EMBC 2009. Annual International Conference of the IEEE
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-3296-7
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2009.5334132