Title :
Modeling molecular communications at NANO-SCALE with applications in medicine and microbiology
Author :
Wysocki, Tadeusz A.
Author_Institution :
Univ. of Nebraska-Lincoln, Lincoln, NE, USA
Abstract :
Summary form only given. Many biological processes that happen at the cellular level can be considered as information transfer, which is the area of telecommunications research. Examples: Gene delivery, targeted drug delivery, viral infections, cell metabolic processes, etc. Developing an accurate but simple simulation model can significantly speedup analysis of those processes and reduce expenses associated with laboratory experiments. It can also help in identifying bottlenecks in signaling pathways and facilitate studying cell responses to changes in underlying conditions (e.g. initial concentrations of proteins, changing reaction speeds, etc.). We propose to use a telecommunications modeling approach based on queuing theory and stochastic modeling to build simulation models tailored to particular biological/medical application. In the presentation, the fundamental aspects of the modelling as well as some of the developed models will be presented and results of simulations compared with the available experimental data.
Keywords :
biomedical communication; cellular biophysics; molecular communication (telecommunication); queueing theory; stochastic processes; biological processes; cell metabolic processes; cellular level; gene delivery; information transfer; medicine; microbiology; molecular communication modelling; nano-scale; queuing theory; signaling pathways; stochastic modeling; targeted drug delivery; telecommunications modeling approach; viral infections; Analytical models; Biological system modeling; Data models; Educational institutions; Molecular communication; Nanobioscience; Telecommunications;
Conference_Titel :
Signal Processing and Communication Systems (ICSPCS), 2014 8th International Conference on
Conference_Location :
Gold Coast, QLD
DOI :
10.1109/ICSPCS.2014.7021048