Title :
Pharmacology evaluation of Litsea garciae (Lauraceae)
Author :
Kutoi, Clifford Junaidi ; Yen, Khong Heng ; Seruji, Nurr Maria Ulfa
Author_Institution :
School of Chemistry and Environmental Studies, Faculty of Applied Sciences, University Teknologi MARA, Jalan Meranek, 94300 Kota Samarahan, Sarawak, Malaysia
Abstract :
Litsea graciae is used by local communities as an antidote against snake, centipede and scorpion bite. It is also used to treat muscular pains, sprained ankles and knees, skin disease and blood in stools. The methanolic crude samples of leaves, barks and fruits were tested for cytotoxic and anti-inflammatory. Cytotoxicity against Cervical Cancer (HeLa), Human Breast Cancer (MCF-7) and Human colorectal Cancer (HT-29) cell lines were using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium (MTT) assay and the anti-inflammatory evaluations were conducted based on Lipoxygenase assay, Hyaluronidase assay and Xanthine oxidase assay.
Keywords :
Biochemistry; Communities; Compounds; Educational institutions; Humans; Pharmaceuticals; anti-inflammatory; cytotoxic; lauraceae; litsea garciae;
Conference_Titel :
Business Engineering and Industrial Applications Colloquium (BEIAC), 2012 IEEE
Conference_Location :
Kuala Lumpur, Malaysia
Print_ISBN :
978-1-4673-0425-2
DOI :
10.1109/BEIAC.2012.6226075
