Biological effects and liver biomarkers of PCB contamination on freshwater fish Carassius auratus

Author

Ji, Yong ; Lu, Guanghua

Author_Institution

Coll. of Hydraulic & Ecological Eng., Nanchang Inst. of Technol., Nanchang, China

fYear

2011

fDate

24-26 June 2011

Firstpage

5767

Lastpage

5770

Abstract

Fresh fish Carassius auratus were chosen as experimental animals to study the potential of biological effects after fish were injected with different dose (0.001, 0.006, 0.03, 0.16, 0.78 mg/kg) of polychlorinated biphenyls (PCB). The hepatic biochemical responses to medium-term exposure of PCB were measured as reduced glutathione (GSH) and malondialdehyde (MDA) to assess sub-lethal effects. Clear dose-response relationships were found for liver GSH and MDA content of all concentrations. In most case, time dependence was apparent at higher concentration of 0.03 mg/kg. GSH and MDA in Carassius auratus were confirmed as useful biomarkers of exposure to PCB.

Keywords

aquaculture; biological tissues; biotechnology; genetic engineering; organic compounds; water pollution; Carassius auratus; PCB contamination; biological effects; freshwater fish; hepatic biochemical responses; liver biomarkers; malondialdehyde; polychlorinated biphenyls; reduced glutathione; sub-lethal effects; Biochemistry; Chemicals; Lipidomics; Liver; Marine animals; Stress; Biomarker; Carassius auratus; GSH; MDA;

fLanguage

English

Publisher

ieee

Conference_Titel

Remote Sensing, Environment and Transportation Engineering (RSETE), 2011 International Conference on

Conference_Location

Nanjing

Print_ISBN

978-1-4244-9172-8

Type

conf

DOI

10.1109/RSETE.2011.5965664

Filename

5965664