Development and evaluation of a multi-wavelength multi-channel time resolved optical instrument for NIR/MRI mammography co-registration

Author

Intes, Xavier ; Yu, Jiangsheng ; Yodh, Arjun G. ; Chance, Britton

Author_Institution

Dept. of Biochem. & Biophys., Pennsylvania Univ., Philadelphia, PA, USA

fYear

2002

fDate

2002

Firstpage

91

Lastpage

92

Abstract

We have developed a multi-channel/multi-wavelength photon counting instrument to perform near infrared diffuse optical spectroscopy and tomography simultaneously with a magnetic resonance scanner. The instrument has been tested with phantoms mimicking relevant breast configurations. Accuracy limits of absolute and relative optical properties determination are analyzed. Then, clinical in-vivo preliminary results are presented

Keywords

bio-optics; biomedical MRI; image registration; infrared imaging; infrared spectroscopy; laser applications in medicine; mammography; medical image processing; optical tomography; photon counting; time resolved spectroscopy; tumours; turbidity; NIR/MRI mammography coregistration; absolute optical properties; accuracy limits; blood saturation; blood volume; breast phantoms; breast tumor; contrast agent; diffuse optical tomography; intrinsic chromophores; isotropic point source; magnetic resonance scanner; multichannel multiwavelength photon counting instrument; near infrared diffuse optical spectroscopy; noninvasive technology; photon density waves; photon migration; relative optical properties; time curve; time resolved optical instrument; turbid media; Biomedical optical imaging; Equations; Infrared spectra; Instruments; Mammography; Optical attenuators; Optical saturation; Optical scattering; Optical sensors; Single photon emission computed tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 2002. Proceedings of the IEEE 28th Annual Northeast

Conference_Location

Philadelphia, PA

Print_ISBN

0-7803-7419-3

Type

conf

DOI

10.1109/NEBC.2002.999480

Filename

999480