The impact of variations in membrane capacitance on the detected neural-electronic signal

There have been various theoretical and experimental studies presented in the literature that focus on interfacing neurons with discrete electronic devices such as transistors. The demonstrated lack of reproducible fidelity of the nerve cell action potential at the device junction would make it impractical to implement these devices in any neural prosthetic application where reliable detection of the action potential was a pre-requisite. In this study, the impact of typical variations in membrane capacitance on the detected neural signal is investigated.