Diagnosis of breast cancer using auto fluorescence and diffuse reflectance spectroscopy

Author

Ramanujam, N. ; Palmer, G. ; Breslin, T. ; Gichrist, K.

Author_Institution

Dept. of Biomed. Eng., Wisconsin Univ., Madison, WI, USA

Volume

3

fYear

2002

fDate

23-26 Oct. 2002

Firstpage

2279

Abstract

Proof-of-principle studies were carried out to assess the diagnostic potential of auto fluorescence and diffuse reflectance spectroscopy for discriminating between malignant and non-malignant breast tissues, ex vivo. Auto fluorescence spectra at excitation wavelengths of 300,320 and 340 nm were found to be most effective in differentiating malignant (13) from non-malignant tissues (25) in this pilot investigation.

Keywords

bio-optics; biological organs; cancer; fluorescence spectroscopy; gynaecology; patient diagnosis; reflectivity; 300 to 340 nm; auto fluorescence; breast cancer diagnosis; diagnostic potential; diffuse reflectance spectroscopy; excitation wavelengths; malignant breast tissues; nonmalignant breast tissues; pilot investigation; proof-of-principle studies; tissues discrimination; Biomedical optical imaging; Breast cancer; Fluorescence; Needles; Optical feedback; Optical sensors; Probes; Reflectivity; Spectroscopy; Wavelength measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint

ISSN

1094-687X

Print_ISBN

0-7803-7612-9

Type

conf

DOI

10.1109/IEMBS.2002.1053281

Filename

1053281