DocumentCode
2495571
Title
A Non-Random Gait through the Human Genome
Author
Huang, Moli ; Zhu, Huangqiong ; Shen, Bairong ; Gao, Ge
Author_Institution
Center for Syst. Biol., Soochow Univ., Suzhou, China
fYear
2009
fDate
11-13 June 2009
Firstpage
1
Lastpage
3
Abstract
With the accumulation of genomic data, it is increasingly clear that eukaryotic genes do not randomly distribute in chromosomes. In this study, we investigated the distribution of 27142 genes mapped at whole chromosomes reported in the Human Genome Data Base as of January 2007. We provide first evidence that distances of neighbour genes follow normal distribution after data transformation. Moreover, our studies first reveal that intergenic distances on every chromosome are convergent to one stationary value.
Keywords
biology computing; cellular biophysics; genomics; chromosomes; eukaryotic genes; human genome; intergenic distances; nonrandom gait; Bioinformatics; Biological cells; Biomedical engineering; Convergence; Gaussian distribution; Genomics; Humans; Laboratories; Systems biology; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009. 3rd International Conference on
Conference_Location
Beijing
Print_ISBN
978-1-4244-2901-1
Electronic_ISBN
978-1-4244-2902-8
Type
conf
DOI
10.1109/ICBBE.2009.5162209
Filename
5162209
Link To Document