Protein Folding Structure Prediction based on Distance Distribution and Dihedral Angle Distribution

The continuous physical-mathematical model of the 3D structures of protein has been obtained by analyzed the 3D structures of biological protein according to the distance and dihedral angle distribution of amino acid residue conforming to Boltzmann theorem. On this foundation, stretches of the B (D) main chain for the bovine insulin have been calculated by application of the improved simulated annealing algorithm. The consistency of stretches and space folded structure for protein has been proved by edited protein sequences 1RPB folded prediction program. The global lowest energy has been calculated by amino acid sequence and a better convergence effect has been achieved.