DocumentCode
2552317
Title
Analysis of the Topological Characteristics of a Protein-Protein Interaction Network
Author
Sun, Yuanyuan ; Zhao, Yujie ; Tse, Chi K. ; Lau, Francis C M
Author_Institution
Coll. of Comput. Sci. & Technol., DaLian Univ. of Technol., Dalian, China
fYear
2012
fDate
18-21 Oct. 2012
Firstpage
127
Lastpage
130
Abstract
The Protein-Protein Interaction networks are the typical complex biological networks, and the analysis of their topological characteristics is one of the most important and widely discussed research topics today. This paper analyzes the topological characteristics of a PPI network based on the theory of complex networks, focusing on degree distribution, average path length, network diameter, clustering coefficient, degree correlations as well as fractality. The experimental results show that this PPI network has the typical scale-free and small-world distributions, low clustering coefficient, negative correlation, but it has no fractal feature.
Keywords
molecular biophysics; proteins; small-world networks; topology; PPI network; average path length; clustering coefficient; complex biological networks; complex networks; degree correlations; degree distribution; fractality; network diameter; protein-protein interaction network; scale-free distributions; small-world distributions; topological characteristics; Complex networks; Correlation; Educational institutions; Fractals; Niobium; Proteins; PPI networks; correlations; fractal; scale-free; small-world; topological analysis;
fLanguage
English
Publisher
ieee
Conference_Titel
Chaos-Fractals Theories and Applications (IWCFTA), 2012 Fifth International Workshop on
Conference_Location
Dalian
Print_ISBN
978-1-4673-2825-8
Type
conf
DOI
10.1109/IWCFTA.2012.36
Filename
6383260
Link To Document