• DocumentCode
    2552317
  • Title

    Analysis of the Topological Characteristics of a Protein-Protein Interaction Network

  • Author

    Sun, Yuanyuan ; Zhao, Yujie ; Tse, Chi K. ; Lau, Francis C M

  • Author_Institution
    Coll. of Comput. Sci. & Technol., DaLian Univ. of Technol., Dalian, China
  • fYear
    2012
  • fDate
    18-21 Oct. 2012
  • Firstpage
    127
  • Lastpage
    130
  • Abstract
    The Protein-Protein Interaction networks are the typical complex biological networks, and the analysis of their topological characteristics is one of the most important and widely discussed research topics today. This paper analyzes the topological characteristics of a PPI network based on the theory of complex networks, focusing on degree distribution, average path length, network diameter, clustering coefficient, degree correlations as well as fractality. The experimental results show that this PPI network has the typical scale-free and small-world distributions, low clustering coefficient, negative correlation, but it has no fractal feature.
  • Keywords
    molecular biophysics; proteins; small-world networks; topology; PPI network; average path length; clustering coefficient; complex biological networks; complex networks; degree correlations; degree distribution; fractality; network diameter; protein-protein interaction network; scale-free distributions; small-world distributions; topological characteristics; Complex networks; Correlation; Educational institutions; Fractals; Niobium; Proteins; PPI networks; correlations; fractal; scale-free; small-world; topological analysis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Chaos-Fractals Theories and Applications (IWCFTA), 2012 Fifth International Workshop on
  • Conference_Location
    Dalian
  • Print_ISBN
    978-1-4673-2825-8
  • Type

    conf

  • DOI
    10.1109/IWCFTA.2012.36
  • Filename
    6383260