DocumentCode
256765
Title
Dimensionality Reduction for Prostate Cancer
Author
Yanhong Huang ; Guirong Weng
Author_Institution
Sch. of Mech. & Electr. Eng., Soochow Univ., Suzhou, China
Volume
2
fYear
2014
fDate
26-27 Aug. 2014
Firstpage
262
Lastpage
265
Abstract
Oncogene is a kind of inherent genes exists in humans´ cells. It has been recognized as a genetic disease, if the cells activated, it can make a person carcinogenesis. So, the research of digging out the useful information from gene chip is very hot in modern society. The sample size is small, high dimension, nonlinear which causes the ´dimension disaster´, so dimensionality reduction becomes the key point of prostate tumors´ classification. This paper uses Sparse principle component analysis (SPCA), Laplacian Eigenmaps and Generalized Discriminant Analysis (GDA) to classify the prostate tumors, then Support Vector Machine(SVM) is used to classify the data. Due to the experiment data, GDA gets the best result.
Keywords
cancer; eigenvalues and eigenfunctions; medical diagnostic computing; pattern classification; principal component analysis; support vector machines; tumours; GDA; Laplacian eigenmaps; SPCA; SVM; carcinogenesis; data classification; dimension disaster; dimensionality reduction; gene chip; generalized discriminant analysis; genetic disease; inherent genes; oncogene; prostate cancer; prostate tumor classification; sparse principle component analysis; support vector machine; Accuracy; Equations; Kernel; Laplace equations; Mathematical model; Support vector machines; Vectors; Dimensionality reduction; SVM; classification; prostate cancer;
fLanguage
English
Publisher
ieee
Conference_Titel
Intelligent Human-Machine Systems and Cybernetics (IHMSC), 2014 Sixth International Conference on
Conference_Location
Hangzhou
Print_ISBN
978-1-4799-4956-4
Type
conf
DOI
10.1109/IHMSC.2014.165
Filename
6911496
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