• DocumentCode
    256765
  • Title

    Dimensionality Reduction for Prostate Cancer

  • Author

    Yanhong Huang ; Guirong Weng

  • Author_Institution
    Sch. of Mech. & Electr. Eng., Soochow Univ., Suzhou, China
  • Volume
    2
  • fYear
    2014
  • fDate
    26-27 Aug. 2014
  • Firstpage
    262
  • Lastpage
    265
  • Abstract
    Oncogene is a kind of inherent genes exists in humans´ cells. It has been recognized as a genetic disease, if the cells activated, it can make a person carcinogenesis. So, the research of digging out the useful information from gene chip is very hot in modern society. The sample size is small, high dimension, nonlinear which causes the ´dimension disaster´, so dimensionality reduction becomes the key point of prostate tumors´ classification. This paper uses Sparse principle component analysis (SPCA), Laplacian Eigenmaps and Generalized Discriminant Analysis (GDA) to classify the prostate tumors, then Support Vector Machine(SVM) is used to classify the data. Due to the experiment data, GDA gets the best result.
  • Keywords
    cancer; eigenvalues and eigenfunctions; medical diagnostic computing; pattern classification; principal component analysis; support vector machines; tumours; GDA; Laplacian eigenmaps; SPCA; SVM; carcinogenesis; data classification; dimension disaster; dimensionality reduction; gene chip; generalized discriminant analysis; genetic disease; inherent genes; oncogene; prostate cancer; prostate tumor classification; sparse principle component analysis; support vector machine; Accuracy; Equations; Kernel; Laplace equations; Mathematical model; Support vector machines; Vectors; Dimensionality reduction; SVM; classification; prostate cancer;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Intelligent Human-Machine Systems and Cybernetics (IHMSC), 2014 Sixth International Conference on
  • Conference_Location
    Hangzhou
  • Print_ISBN
    978-1-4799-4956-4
  • Type

    conf

  • DOI
    10.1109/IHMSC.2014.165
  • Filename
    6911496