Title :
3D cell patterning method for bio-actuated microsystem using cultured cardiomyocytes
Author :
Morishima, Keisuke ; Tanaka, Yo ; Ebara, Mitsuhiro ; Shimizu, Tatsuya ; Yamato, Masayuki ; Kikuchi, Akihiko ; Sato, Kiichi ; Okan, Teruo ; Kitamori, T.
Author_Institution :
Kanagawa Acad. of Sci. & Technol., Japan
Abstract :
We report the creation and the actuation of hybrid microsystem comprised of a soft material structure and cultured cardiomyocytes using 3D cell patterning technique and pattern transfer method we have developed. This paper introduces a concept for the integrated bio-actuated microsystem for miniaturized chemical and biochemical analysis system. The fabrication of a bio-actuated microsystem using cells, cell patterning technique and experimental system is shown.
Keywords :
biochemistry; biomembranes; biomimetics; biosensors; cardiology; cellular biophysics; microactuators; polymers; 3D cell patterning; bioMEMS actuator; biomembranes; biomimetics; cultured cardiomyocytes; hybrid microsystem actuation; hybrid microsystem creation; integrated bioactuated microsystem; miniaturized biochemical analysis; miniaturized chemical analysis; pattern transfer; soft material structure; Biochemical analysis; Biological materials; Biomedical materials; Biomembranes; Cardiology; Cells (biology); Chemical analysis; Materials science and technology; Microstructure; Scanning electron microscopy;
Conference_Titel :
Microprocesses and Nanotechnology Conference, 2003. Digest of Papers. 2003 International
Conference_Location :
Tokyo, Japan
Print_ISBN :
4-89114-040-2
DOI :
10.1109/IMNC.2003.1268775
