Title :
Potentiometric method for resistance´s measurement of pyrazinamide in mycobacterium tuberculosis
Author :
Furukawa, Roberto ; Rueda, Daniel ; Zimic, Mirko
Author_Institution :
Mech. Eng. Sect., Pontifical Catholic Univ. of Peru, Lima, Peru
Abstract :
An experimental research of the drug pyrazinamide is analyzed and tested with potentiometric method. By understanding the biomechatronic system, consisted of a mechanism of action of the drug Pyrazinamide in a biological system, and an electrical signals, voltametric measures, a method to detect resistance to this specific drug is developed and tested firstly in vitro, then in cultures and finally in decontaminated sputum.
Keywords :
bioelectric phenomena; diseases; drugs; electric resistance measurement; organic compounds; biological system; biomechatronic system; decontaminated sputum; drug pyrazinamide; electrical signals; mycobacterium tuberculosis; potentiometric method; resistance measurement; voltametric measurement; Biochemistry; Correlation; Drugs; Educational institutions; Electrodes; Immune system; Strain;
Conference_Titel :
Biomedical Robotics and Biomechatronics (2014 5th IEEE RAS & EMBS International Conference on
Conference_Location :
Sao Paulo
Print_ISBN :
978-1-4799-3126-2
DOI :
10.1109/BIOROB.2014.6913876
