Title :
MEMS-based biochip for the characterization of single red blood cell
Author :
Cho, Y.H. ; Takama, N. ; Yamamoto, T. ; Fuji, T. ; Kim, B.J.
Author_Institution :
Inst. of Ind. Sci., Tokyo Univ., Japan
Abstract :
We introduce a novel biosensor device for various biocell measurements by singular cell level with parallel analysis and high throughput. This paper deals with the details of its fabrication, including device packaging, and the practical measurement of red blood cells using a twin microcantilever type sensor array. Based on a simple measurement of the electrical impedance of a living single red blood cell and its suspension, an important set of data, which can be used to describe living matter, could be obtained.
Keywords :
bioelectric phenomena; biological techniques; biosensors; blood; cellular biophysics; electric impedance measurement; MEMS-based biochip; biocell measurement; biosensor device; cell suspension; device packaging; electrical impedance measurement; high throughput device; parallel analysis; single red blood cell characterization; twin microcantilever type sensor array; Biosensors; Cells (biology); Diseases; Electrodes; Fabrication; Impedance measurement; Packaging; Red blood cells; Sensor arrays; Throughput; electrical impedance; red blood cell; twin microcantilever type sensor array;
Conference_Titel :
Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on
Print_ISBN :
0-7803-8711-2
DOI :
10.1109/MMB.2005.1548384
