Title :
Synchronization control for circadian rhythm of drosophila with flatness-based adaptive control
Author :
Kusumi, Tetsuya ; Ohmori, Hiromitsu
Author_Institution :
Keio Univ., Tokyo
Abstract :
Developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.
Keywords :
adaptive control; closed loop systems; medicine; molecular biophysics; synchronisation; zoology; Drosophila; circadian rhythm disorder; circadian rhythm restoration; close-loop control; flatness-based adaptive control; medicine; molecular biology; pharmacology; synchronization control; system biology; Adaptive control; Biological control systems; Biological system modeling; Cancer; Cells (biology); Circadian rhythm; Control systems; Neoplasms; Systems biology; Temperature; Adaptive control; Circadian rhythm; Flatness-based control; Synchronization control; System biology;
Conference_Titel :
SICE, 2007 Annual Conference
Conference_Location :
Takamatsu
Print_ISBN :
978-4-907764-27-2
Electronic_ISBN :
978-4-907764-27-2
DOI :
10.1109/SICE.2007.4421177
