• DocumentCode
    2673280
  • Title

    Low-frequency dynamics of functional proteins studied by terahertz time-domain spectroscopy

  • Author

    Yamamoto, Naoki ; Zhang, Feng ; Tamura, Atsuo ; Tominag, Keisuke

  • Author_Institution
    Mol. Photoscience Res. Center, Kobe Univ., Kobe, Japan
  • fYear
    2011
  • fDate
    2-7 Oct. 2011
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    We applied terahertz time-domain spectroscopy on myosin II subfragment 1 (S1) to monitor temperature and hydration dependence of its low-frequency dynamics. In the absorption spectra of both apo and holo S1 (ATP-free and bound form, respectively), so-called dynamical transition was observed at around 190 K only when they are hydrated.
  • Keywords
    DNA; monitoring; proteins; solvation; terahertz spectroscopy; ATP-free; DNA; absorption spectra; apo S1; bound form; dynamical transition; functional protein low-frequency dynamic; holo S1; hydration dependence; myosin II S1; myosin II subfragment1; temperature monitoring; terahertz time-domain spectroscopy; Absorption; Dynamics; Proteins; Spectroscopy; Temperature dependence; Temperature measurement; Time domain analysis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Infrared, Millimeter and Terahertz Waves (IRMMW-THz), 2011 36th International Conference on
  • Conference_Location
    Houston, TX
  • ISSN
    2162-2027
  • Print_ISBN
    978-1-4577-0510-6
  • Electronic_ISBN
    2162-2027
  • Type

    conf

  • DOI
    10.1109/irmmw-THz.2011.6104944
  • Filename
    6104944