Title :
Simulation studies on the dynamics of diabetes mellitus
Author :
Erzen, Fetanet Ceylan ; Birol, Gülnur ; Çinar, Ali
Author_Institution :
Dept. of Chem. & Environ. Eng., Illinois Inst. of Technol., Chicago, IL, USA
Abstract :
Glucose-insulin interaction in an insulin-dependent diabetic patient has been simulated using an overall and a detailed model based on pharmacokinetic diagrams of insulin and glucose. Both models are capable of predicting the blood glucose and insulin levels, total glucose uptake and the renal glucose excretion. The simulator is integrated with a graphical user interface to provide a user-friendly environment. The package may be used to perform virtual experiments with various characteristics, diet and exercise conditions
Keywords :
biochemistry; blood; digital simulation; diseases; graphical user interfaces; medical computing; organic compounds; physiological models; blood glucose level; blood insulin level; detailed model; diabetes mellitus dynamics; diet; exercise conditions; glucose-insulin interaction; insulin-dependent diabetic patient; overall model; pharmacokinetic diagrams; renal glucose excretion; total glucose uptake; user-friendly environment; virtual experiments; Biochemistry; Blood; Cells (biology); Chemical technology; Diabetes; Insulin; Liver; Mathematical model; Pancreas; Sugar;
Conference_Titel :
Bio-Informatics and Biomedical Engineering, 2000. Proceedings. IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
0-7695-0862-6
DOI :
10.1109/BIBE.2000.889612
