DocumentCode :
2713395
Title :
Development of a transduction circuit for piezoresistive MEMS sensor for biosensing
Author :
Abdullah, M.F. ; Khuan, L.Y. ; Madzhi, N.K. ; Masrie, M. ; Ahmad, A.
Author_Institution :
Fac. of Electr. Eng., Univ. Teknol. MARA, Shah Alam, Malaysia
Volume :
2
fYear :
2009
fDate :
4-6 Oct. 2009
Firstpage :
679
Lastpage :
683
Abstract :
This paper concerns the development of a potentiometric transduction circuit for a piezoresistive MEMS sensor to detect human stress. The biosensor is comprised of a bioreceptor and a transducer. The sensing principle is based on immobilization of the bioreceptor to produce a biochemical reaction. The novel piezoresistive microcantilever sensor integrated with a transduction circuit converts this biochemical event into a measurable electrical signal. From previous work, it has been found that the level of alpha amylase activity corresponds to human stress. The piezoresistive MEMS sensing and transduction method are described, with enzyme concentration as the input and voltage as the output. The transduction circuit designed enables the small change in resistivity due to the enzymatic reaction to be detected. The circuit has been designed and tested through theoretical, simulation and experimental studies. It has been found that for a sensor input range of 1.2 to 1.3 kilo ohms, an output range of -100 to +100 millivolts is obtained. A discrepancy within 3.69% is found between simulation and experimental results, on the average. The null bridge condition is designed at 1.2 kilo ohms while the offset rate is found to be 10 millivolts per ohm.
Keywords :
bioMEMS; biochemistry; bioelectric potentials; biosensors; enzymes; microsensors; piezoresistive devices; alpha amylase activity; biochemical reaction; bioreceptor; biosensing; biosensor; electrical signal; enzyme concentration; human stress detection; immobilization; null bridge; piezoresistive MEMS sensor; piezoresistive microcantilever sensor; potentiometric transduction circuit; Biosensors; Circuit simulation; Circuit testing; Electric variables measurement; Humans; Integrated circuit measurements; Micromechanical devices; Piezoresistance; Stress; Transducers; Human Stress; Piezoresistive MEMS Sensor; Potentiometric; Salivary Alpha Amylase; Transduction;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Industrial Electronics & Applications, 2009. ISIEA 2009. IEEE Symposium on
Conference_Location :
Kuala Lumpur
Print_ISBN :
978-1-4244-4681-0
Electronic_ISBN :
978-1-4244-4683-4
Type :
conf
DOI :
10.1109/ISIEA.2009.5356373
Filename :
5356373
Link To Document :
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