Title :
Integrated Fluorescence Sensing for Lab-on-a-chip Devices
Author :
Ji, Honghao ; Dandin, Marc ; Abshire, Pamela ; Smela, Elisabeth
Author_Institution :
Dept. of Electr. Eng., Maryland Univ., College Park, MD
Abstract :
A low noise optical sensor and biocompatible microscale optical filters for integrated fluorescence sensors were developed and tested. The sensor was fabricated in a 0.5 mum CMOS process. The measured reset noise of the sensor is reduced by a factor of 10 compared to conventional active pixel sensors. The transmission ratio in the pass-band and suppression ratio in the stop-band of the optical filters are comparable to that of macroscopic commercial filters for fluorescence microscopy
Keywords :
CMOS integrated circuits; bioMEMS; biological techniques; biosensors; fluorescence; lab-on-a-chip; microsensors; optical filters; optical sensors; 0.5 mum; CMOS; biocompatible microscale optical filters; fluorescence microscopy; fluorescence sensors; integrated fluorescence sensing; lab-on-a-chip devices; low noise optical sensor; pass-band; stop-band; suppression ratio; transmission ratio; Biosensors; CMOS process; Fluorescence; Lab-on-a-chip; Noise measurement; Optical filters; Optical microscopy; Optical noise; Optical sensors; Testing;
Conference_Titel :
Life Science Systems and Applications Workshop, 2006. IEEE/NLM
Conference_Location :
Bethesda, MD
Print_ISBN :
1-4244-0277-8
Electronic_ISBN :
1-4244-0278-6
DOI :
10.1109/LSSA.2006.250392
